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各种肾脏疾病持续进展,到最后都可发展为慢性肾功能不全。过去认为肾功能减退后由于蛋白质代谢产物(尿素、肌酐、尿酸等)潴留,引起尿毒症的各种症状。现在认为激素、多肽等中分子物质起着很大作用。各种慢性肾脏病在基础病变静止后,肾功能仍会持续减退,对此过程的解释有几种学说。
A variety of kidney disease continued to progress, can eventually develop into chronic renal insufficiency. In the past that due to renal dysfunction due to protein metabolites (urea, creatinine, uric acid, etc.) retention, causing a variety of symptoms of uremia. Now that hormones, peptides and other molecular substances play a significant role. A variety of chronic kidney disease in the basic lesions at rest, renal function will continue to decline, explain the process of several theories.