新生儿窒息后有肾损害临床表现不典型，如果及早发现，积极治疗能很快恢复。但目前临床普遍应用的以氮质血症及肌酐升高为肾功能损伤的指标并不灵敏，不能早期发现肾损害。我科对１９９９年１０月～２００１年３月收住的围产期窒息新生儿４０例进行尿酶的测定，现报道如下。对 Neonatal asphyxia kidney damage clinical manifestations are not typical, if found early, aggressive treatment can be quickly restored. However, the common clinical use of azotemia and creatinine increased renal injury index is not sensitive, can not be found early renal damage. Our department on October 1999 ~ March 2001 admitted to the perinatal asphyxia neonatal 40 cases of urease determination are reported below. Correct