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目的分析研究联合使用血栓通注射液与高压氧对脑梗死患者的血脂及血液流变学的影响。方法选择2012年8月—2014年4月杨凌示范区医院收治的脑梗死患者92例为研究对象,随机分为两组。对照组给予高压氧治疗,实验组给予高压氧联合血栓通注射液治疗,观察患者血脂及血液流变学指标的变化。结果治疗后,实验组患者三酰甘油(TG)、总胆固醇(TC)、低密度脂蛋白胆固醇(LDL-C)、脂蛋白a(LP-a)均显著低于对照组患者,高密度脂蛋白胆固醇(HDL-C)显著高于对照组,差异有统计学意义(P<0.05)。实验组与对照组患者治疗后的载脂蛋白A1(Apo A1)、载脂蛋白B(Apo B)对比差异无统计学意义。治疗后,实验组患者血浆黏度、红细胞压积(Hct)及血沉(ESR)均低于对照组患者,差异有统计学意义(P<0.05)。结论联合使用高压氧与血栓通注射液有助于改善脑梗死患者的血脂和血液流变学,具有积极的临床意义。
Objective To study the effects of Xueshuantong injection combined with hyperbaric oxygen on blood lipids and hemorheology in patients with cerebral infarction. Methods A total of 92 patients with cerebral infarction admitted to Yangling Demonstration Area Hospital from August 2012 to April 2014 were selected as study subjects and randomly divided into two groups. The control group was given hyperbaric oxygen therapy. The experimental group was given hyperbaric oxygen combined with Xueshuantong injection, and the changes of blood lipid and hemorheology indexes were observed. Results After treatment, the TG, TC, LDL-C and LP-a in the experimental group were significantly lower than those in the control group. The levels of high density lipids The level of HDL-C was significantly higher than that of the control group (P <0.05). The experimental group and control group patients after treatment of apolipoprotein A1 (Apo A1), apolipoprotein B (Apo B) the difference was not statistically significant. After treatment, the plasma viscosity, hematocrit (Hct) and erythrocyte sedimentation rate (ESR) in the experimental group were lower than those in the control group, the difference was statistically significant (P <0.05). Conclusion Combined use of hyperbaric oxygen and Xueshuantong injection can help to improve the blood lipid and hemorheology in patients with cerebral infarction. It has a positive clinical significance.