脓毒症(sepsis)是感染、创伤及外科大手术后的常见并发症。攻克脓毒症是世界一大难题。脓毒症病情凶险,病死率高达28%-47%[1],治疗成本高昂,发病率呈逐年增长。近10年来脓毒症的实验与临床研究方兴未艾,脓毒症动物模型是研究脓毒症发病机制和临床防治所必须的实验平台,同时也 Sepsis is a common complication after infection, trauma and major surgery. Overcoming sepsis is a major problem in the world. Severe sepsis, the case fatality rate as high as 28% -47% [1], the high cost of treatment, the incidence increased year by year. Nearly 10 years of experimental and clinical sepsis in the ascendant, animal models of sepsis is to study the pathogenesis of sepsis and clinical prevention and control of the necessary experimental platform, but also