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采用进食100g标准面粉馒头餐方法（相当于75g葡萄糖）对正常人（对照组）、胰岛素依赖型糖尿病（IDDM）、非胰岛素依赖型糖尿病（NIDDM）、葡萄糖耐量异常（IGT）患者进行胰岛素（INS）、C肽（CPR）动态观察。结果表明：（1）IDDM患者INS、CPR分泌显著低于对照组（P＜0．01）．是绝对不足；（2）NIDDM患者INS、CPR达峰值时间明显落后于对照组（P＜0．01），显示出NIDDM的重要特征；（3）IGT患者达峰值时间在对照组与NIDDM组之间，说明其胰岛B细胞分泌功能受损；（4）小部分NIDDM患者的CPR空腹值与IDDM组相近（P＞0．05），峰值明显低于NIDDM组（P＜0．01），但高于IDDM组（P＜0．01），预示其中可能存在相当数量的缓慢进展型IDDM。
Insulin (INS) was administered to normal subjects (control group), insulin-dependent diabetes mellitus (IDDM), non-insulin dependent diabetes mellitus (NIDDM) and impaired glucose tolerance (IGT) ), C peptide (CPR) dynamic observation. The results showed that: (1) INS and CPR secretion in IDDM patients was significantly lower than that in control group (P <0.01). (2) The peak time of INS and CPR in NIDDM patients lagged behind the control group (P <0.01), showing the important characteristics of NIDDM; (3) The peak time of IGT patients in the control group and NIDDM group (4) The CPR fasting value of a small number of NIDDM patients was similar to that of IDDM group (P> 0.05), and the peak value was significantly lower than that of NIDDM group (P <0.01) Higher than IDDM group (P <0.01), indicating that there may be a considerable number of slowly progressing IDDM.