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一氧化氮是一种具有广泛生物活性的小分子化合物,一氧化氮合酶是一氧化氮合成的关键酶。近看来,一氧化氮及一氧化氮合酶在卵巢癌细胞中的产生和表达与肿瘤细胞的增殖、转移和凋亡的关系日益引起人们重视。本文就一氧化氮及其合酶和卵巢癌的作用关系作一综述。
Nitric oxide is a small molecule compound with a wide range of biological activities. Nitric oxide synthase is a key enzyme in the synthesis of nitric oxide. Recently, the relationship between the production and expression of nitric oxide and nitric oxide synthase in ovarian cancer cells and the proliferation, metastasis and apoptosis of tumor cells is attracting more and more attention. This article reviews the relationship between nitric oxide and its synthase and ovarian cancer.