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目的探讨分析完整结肠系膜切除治疗高龄结肠癌患者的临床效果及生存情况。方法选择2014年1月至2016年12月进行治疗的64例高龄结肠癌患者作为研究对象,采用随机数字表法将其平均分为两组,各32例,对照组患者应用结肠根治术,观察组患者采用完整结肠系膜切除术,经不同方法治疗后比较两组患者临床效果、并发症的发生情况及术后生存情况。结果观察组临床总有效率(81.25%)与对照组(75.00%)相比差异无统计学意义(P>0.05)。观察组患者术后3、7 d炎性指标改善情况及胃肠功能恢复的情况与对照组患者相比,差异有统计学意义(P<0.05,P<0.01)。观察组患者术后并发症总发生率(12.50%)与对照组(34.38%)相比差异有统计学意义(P<0.05)。观察组患者术后生存情况良好,出院30 d内患者的再入院率及病死率均为0,优于对照组(25.00%,12.50%),差异有统计学意义(P<0.05,P<0.01)。结论对高龄结肠癌患者应用完整结肠系膜切除进行治疗,临床效果显著,可有效改善其炎症反应发生的情况、加快胃肠功能的恢复,同时显著降低术后并发症的发生率及出院30 d内再入院率和病死率。
Objective To investigate the clinical effects and survival of patients with advanced colon cancer treated by complete mesorectal excision. Methods 64 patients with advanced colon cancer who were treated from January 2014 to December 2016 were selected and divided into two groups according to the random number table (32 cases in each group). The patients in the control group were treated by radical mastectomy The patients underwent complete mesorectal excision. The clinical effects, complications and postoperative survival of the two groups were compared after treatment by different methods. Results The total effective rate (81.25%) in the observation group was not significantly different from that in the control group (75.00%) (P> 0.05). Compared with the control group, there was significant difference between the observation group and the control group (P <0.05, P <0.01). The total incidence of postoperative complications in the observation group (12.50%) was significantly different from that in the control group (34.38%) (P <0.05). The survival rate of patients in observation group was good after operation, and the readmission rate and mortality of patients within 30 days after discharge were 0, which was significantly higher than that of control group (25.00%, 12.50%) (P <0.05, P <0.01) ). Conclusion The treatment of advanced colorectal cancer patients with complete mesorectal excision, the clinical effect is significant, which can effectively improve the occurrence of inflammatory reactions and speed up the recovery of gastrointestinal function, while significantly reducing the incidence of postoperative complications and within 30 days after discharge Readmission rates and fatality rates.