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目的:观察补阳还五汤佐治慢性肺心病的疗效及其对血液流变学指标的影响。方法:随机将80例慢性肺心病患者分为观察组和对照组各40例。对照组给予常规西医治疗,观察组在上述西医治疗基础上加用补阳还五汤口服。两组均治疗30 d。观察治疗前后的血液流变学指标、D-二聚体含量及心肺功能指标的变化。结果:治疗后两组的血液流变学指标及D-二聚体含量均显著优于治疗前(P<0.05或P<0.01);但观察组改善程度显著优于对照组(P<0.05或P<0.01)。治疗后两组的心肺功能及动脉血气指标均显著优于治疗前(P<0.05或P<0.01);但观察组改善程度显著优于对照组(P<0.05或P<0.01)。观察组服用中药后未发生不良反应。结论:补阳还五汤佐治慢性肺心病疗效确切,可降低血液黏度,改善心肺功能,且安全性好。
Objective: To observe the curative effect of Buyang Huanwu Decoction on chronic pulmonary heart disease and its effect on hemorheology indexes. Methods: 80 cases of chronic pulmonary heart disease were randomly divided into observation group and control group, 40 cases each. The control group was given routine western medicine treatment. The observation group was given Buyang Huanwu decoction orally on the basis of the above western medicine treatment. Both groups were treated for 30 days. The changes of hemorheology, D-dimer and cardiopulmonary function were observed before and after treatment. Results: The hemorrheological indexes and D-dimer contents of the two groups were significantly better than those before treatment (P <0.05 or P <0.01), but the improvement in the observation group was significantly better than that in the control group (P <0.05 or P <0.01). The cardiopulmonary function and arterial blood gas index of the two groups were significantly better than those before treatment (P <0.05 or P <0.01). However, the improvement in the observation group was significantly better than that of the control group (P <0.05 or P <0.01). Observation group after taking the Chinese medicine did not occur adverse reactions. Conclusion: Buyang Huanwu Decoction adjuvant Chronic pulmonary heart disease curative effect is exact, can reduce blood viscosity, improve cardiopulmonary function, and good safety.