由光诱发的皮肤原发刺激样的光毒性作用,其检测方法很少有报道。Kochevar等(1982)成功地用煤焦油组份蒽在豚鼠皮肤上诱发出光毒性。本文考虑到便于与兔皮肤原发刺激检测方法作比较,建立以蒽诱发兔光毒性的测试模型的简便方法,以供筛选直接接触皮肤的化学品,如化妆品及其源料,添加剂以及护肤用品等参考。 Light-induced primary phototoxicity of skin-like stimuli, the detection method is rarely reported. Kochevar et al. (1982) successfully induced phototoxicity on guinea pig skin with anthracene, a coal tar component. In this paper, a simple method to establish a test model of anthracycline-induced phototoxicity in rabbits is proposed to facilitate comparison with primary skin irritation testing methods in rabbits for the screening of chemicals that directly contact the skin, such as cosmetics and their sources, additives and skin care products Other reference.