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高剂量化疗联合自体造血干细胞移植治疗恶性肿瘤失败的主要原因是疾病的复发。目前认为 ,肿瘤细胞随着移植物再次输入人体是导致复发的重要因素。本文综述了近年来用免疫学方法在体外净化自体造血干细胞移植物的一些新进展。
The main reason for the failure of high-dose chemotherapy combined with autologous hematopoietic stem cell transplantation in the treatment of malignant tumors is the relapse of the disease. It is currently believed that tumor cells re-enter the body with the graft is an important factor leading to recurrence. This review summarizes some recent advances in the immunological purification of autologous hematopoietic stem cell grafts in vitro in recent years.