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妇科恶性肿瘤是影响女性健康的主要威胁.相关研究发现,肿瘤转移抑制基因1 (metastasis suppressor1,MTSS1),在宫颈组织中从CIN Ⅰ到宫颈癌,随病变程度增加表达阳性率增加;而在卵巢癌中MTSS1表达的下调与卵巢癌细胞的侵袭性密切相关,其过表达可抑制卵巢癌侵袭性,另有研究发现血细胞中MTSS1表达的下调标志其不良预后;其他妇科恶性肿瘤与MTSS1表达相关性仍需进一步研究.在其他器官恶性肿瘤中,MTSS1呈现为特异性表达.MTSS1在妇科恶性肿瘤中的表达差异可能会对临床诊疗、判断预后以及复诊评估起到指导作用.“,”Gynecological malignant tumor is a major threat to women's health.Related research found that the positive expression rate of metastasis suppressor 1 (MTSS 1) increased in cervical tissue from CIN I to cervical cancer;the downregulation of MTSS1 in ovarian cancer cell is associated with invasiveness and its overexpression can inhibit ovarian cancer invasion,another study found that the expression of MTSS1 in blood cells cut marks the poor prognosis;further study of the correlation between MTSS1 expression and other gynecological malignant tumor is still needed.In other malignant tumors,MTSS1 is expressed as a specific expression.Differential expression of MTSS1 in gynecological malignant tumor may play a guiding role in clinical diagnosis and treatment,judging prognosis and follow-up evaluation.