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高动脉僵硬度似乎参与高血压的发病。该研究旨在验证患高血压父母其后代在临床表现为高血压之前,就体现出较高的动脉僵硬度,毕竟高血压具有遗传性。方法:纳入Framingham心脏研究第三代队列中的1564名非高血压者(平均年龄38岁,55%为女性,其父母是Framingham后代研究受试者),比较动脉张力测量值。结果:最终分别纳入父母均无高血压(对照组)(468人)、父母其中一人患高血压(715人)、父母均
High arterial stiffness seems to be involved in the pathogenesis of hypertension. The aim of this study was to validate that offspring of hypertensive parents show a high degree of arterial stiffness prior to the clinical presentation of hypertension, after all, and hypertension is hereditary. METHODS: A total of 1564 non-hypertensive subjects (mean age 38 years, 55% female, whose parents were Framingham offspring) were enrolled in the Framingham Heart Study Third Generation cohort and arterial tension measurements were compared. Results: In the end, no hypertension was included in the parents (control group) (468), one of the parents was hypertension (715), both parents