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目的 :探讨慢性阻塞性肺病 (COPD)极量运动及其恢复期呼吸方式的改变。方法 :临床稳定期COPD患者 40例和正常中老年男性 2 2例作极量运动负荷试验。以运动及其恢复期潮气量 (VT)作为横座标与分时通气量 (·VE)作为纵座标作图 ,比较运动及其恢复期呼吸方式的改变。结果 :与正常人相比 ,COPD患者△VT显著增加 ,其大小与FEV1%和VEmax/MVV明显相关 ,但与 ·VO2 max、·VO2 max/Pred·VO2 max、HRmax、SaO2 min、VTmax、EqO2 max、EqCO2 max等无明显的相关性。结论 :临床稳定期COPD患者极量运动恢复期存在浅快呼吸 ,其发生可能与呼吸肌疲劳等有关。
Objective: To explore the changes of respiratory system during the extremes of chronic obstructive pulmonary disease (COPD) and its recovery. Methods: 40 stable COPD patients and 22 normal middle-aged men were included in the maximal exercise load test. The exercise and its recovery tidal volume (VT) were plotted as abscissa and time-varying ventilation (· VE) as the ordinate, and the change of respiration during exercise and convalescence was compared. Results: Compared with normal subjects, △ VT increased significantly in patients with COPD and its size was significantly correlated with FEV1% and VEmax / MVV, but not significantly different with · VO2max, · VO2max / Pred · VO2max, HRmax, SaO2min, VTmax, EqO2 max, EqCO2 max no significant correlation. Conclusion: There is a shallow breathing in the exacerbation of COPD in stable COPD patients, which may be related to respiratory muscle fatigue.