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目前谷—丙转氨酶释放入血机理还不十分准确,一般认为胞浆中的转氨酶能为组织液正常交换较易逸出,故肝细胞损伤时S—GPT就明显升高,但有的学者认为:酶的释放不一定是肝细胞损伤,而是肝细胞膜改变了通透性是主要原因。亦有学者认为:当肝细胞受损时正常为线粒体结合的谷一丙酶转移到胞浆更易逸出,与细胞膜通透性改变关系不大。动物试验及临床观察,当胆道梗阻S—GPT也常有升高趋势,这就提示酶浓度变异与排法机能相关。血中谷一丙酶的清除与蛋白代谢,灭活作用,与尿和胆汁排泄速度有关。
Currently valium - C transaminase into the blood is not very accurate mechanism is generally believed that the cytoplasm of the aminotransferase for the normal exchange of tissue fluid easier to escape, so the liver cell injury S-GPT increased significantly, but some scholars believe that: The release of enzymes is not necessarily liver cell damage, but the main reason that the permeability of the liver cell membrane changes. Some scholars believe that: when the liver cell damage is normal mitochondrial glutathione enzyme transfer to the cytoplasm easier to escape, and the change of cell membrane permeability has little to do. Animal experiments and clinical observation, when the biliary obstruction S-GPT is also often increased, suggesting that enzyme concentration variation and discharge function related. Blood clearance of a-enzymatic enzymes and protein metabolism, inactivation, and urine and bile excretion rate.