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目的探讨环磷酸腺苷葡甲胺治疗毛细支气管炎的疗效。方法128例毛细支气管炎患儿随机分为治疗组64例和对照组64例,两组患儿均常规给予抗感染、吸氧、雾化、吸痰、止咳、镇静及小剂量激素静脉点滴等综合治疗,治疗组在综合治疗的基础上加用环磷酸腺苷葡甲胺,每次2～5mg/kg,加液静脉点滴,2次/d,疗程7d;观察主要症状、体征消失时间及住院时间。结果治疗组在缓解症状、改善体征、缩短病程等方面优于对照组,差异有统计学意义(P<0.05)。结论环磷酸腺苷葡甲胺治疗小儿毛细支气管炎疗效确切,安全、可靠,可作为小儿毛细支气管炎治疗的首选药物。
Objective To investigate the curative effect of cyclic adenosine monophosphate meglumine hydrochloride on bronchiolitis. Methods A total of 128 children with bronchiolitis were randomly divided into treatment group (64 cases) and control group (64 cases). Both groups were given anti-infection, oxygen inhalation, atomization, suctioning, cough suppression, sedation and intravenous injection of small doses of hormone Combined treatment, the treatment group on the basis of comprehensive treatment with cyclic adenosine monophosphate meglumine, each 2 ~ 5mg / kg, plus intravenous drip, 2 times / d, treatment 7d; observe the main symptoms, signs of disappearance and Hospitalization time. Results The treatment group was better than the control group in relieving symptoms, improving the signs and shortening the course of disease, the difference was statistically significant (P <0.05). Conclusion Cyclophosphamide meglumine is effective, safe and reliable in the treatment of pediatric bronchiolitis, and can be used as the drug of choice for the treatment of pediatric bronchiolitis.