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用血清药理学的方法研究了三黄乙肝胶囊对HBsAg的体外抑制作用。通过酶联免疫吸附测定 (ELISA)发现含三黄乙肝胶囊的家兔血清对HBsAg具有明显的抑制作用 ,随血清中药物浓度的升高、作用时间的延长而增强 ,随HBsAg浓度的升高而减弱 ,三黄乙肝胶囊粗制剂对HBsAg的直接抑制作用更强于含药血清。
The inhibitory effect of Sanhuang Yigan capsule on HBsAg in vitro was studied by serum pharmacology. The sera of rabbits containing Sanhuang Yigan capsules were found to have a significant inhibitory effect on HBsAg by enzyme-linked immunosorbent assay (ELISA), with the increase of drug concentration in the serum and the prolongation of action time, with the increase of HBsAg concentration. Decreased, the direct inhibition of HBsAg by the crude preparation of Sanhuang Yigan Capsule was stronger than that of drug-containing serum.