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[目的]为最大程度改善新生儿缺氧缺血性脑病愈合,评价早期综合干预及康复治疗对新生儿缺氧缺血性脑病治疗价值。[方法]收集2010年8~12月在某院儿科就诊的99例患儿。家长同意患儿出院后接受早期综合干预及康复治疗的,分为观察组;拒绝接受的,分为对照组,仅给予出院后一般康复指导。对两组患儿分别于3月龄、12月龄及21月龄监测发育商数。[结果]观察组与对照组预后情况对照,经χ2检验,χ2值为20.42,差异有统计学意义(P﹤0.01)。观察组与对照组患儿3月龄、12月龄及21月龄的发育商数对照,经t检验,差异有统计学意义(P﹤0.01)。[结论]早期综合干预及康复治疗能有效改善新生儿缺氧缺血性脑病(HIE)患儿的智能发育,显著减少脑瘫等后遗症的发生率,值得在临床上推广。
[Objective] To evaluate the therapeutic effect of early comprehensive intervention and rehabilitation on the neonatal hypoxic-ischemic encephalopathy in order to maximize the improvement of neonatal hypoxic-ischemic encephalopathy. [Methods] A total of 99 pediatric patients treated in a pediatric department from August to December in 2010 were collected. Parents agreed to discharge children after receiving early comprehensive intervention and rehabilitation treatment, divided into observation group; refused to accept, divided into control group, only to give general rehabilitation guidance after discharge. The two groups of children were monitored at 3 months, 12 months and 21 months of age to develop the quotient. [Result] Compared with the control group, the prognosis of the observation group and the control group, χ2 test, χ2 value of 20.42, the difference was statistically significant (P <0.01). There were significant differences between the observation group and the control group in the development quotient of 3-month, 12-month and 21-month old children after t-test (P <0.01). [Conclusion] Early comprehensive intervention and rehabilitation can effectively improve the intelligence development of neonates with hypoxic-ischemic encephalopathy (HIE) and significantly reduce the incidence of cerebral palsy and other sequelae, which is worth popularizing clinically.