背景胰岛素自身免疫综合征(Insulin autoimmune syndrome,IAS)是以无外源性胰岛素摄入时发生自发性低血糖和血清高水平自身反应性胰岛素合并高滴度胰岛素抗体为特点的综合征。其在日本是造成低血糖的第三大主要原因,但在西方国家,该病 Background Insulin autoimmune syndrome (IAS) is a syndrome characterized by spontaneous hypoglycemia without exogenous insulin intake and high serum auto-reactive insulin with high titer of insulin antibody. Its main cause of hypoglycemia in Japan is the third largest, but in western countries, the disease