Synthesis, Characterization and Biological Activities of Novel Water-soluble Metalloporphyrins

来源 :Chinese Chemical Letters | 被引量 : 0次 | 上传用户:sisi_g
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The synthesis, characterization, and biological activities of a series of metal porphyrins were described. The complexes 3a~3e were prepared from the reaction of compound 2 with M(OAc)2 in CHCl3, and the treatment of 3a~3f with pyridine gave corresponding complexes 4a~4f. These new compounds were identified by absorption spectroscopies, 1H NMR and elemental analysis. The results of biological activity testing revealed that 4a and 4c had stronger inhibiting action for Escherichia coli (CCTCC AB91115). The synthesis, characterization, and biological activities of a series of metal porphyrins were described. The complexes 3a-3e were prepared from the reaction of compound 2 with M (OAc) 2 in CHCl3, and the treatments 3a- complexes 4a ~ 4f. These new compounds were identified by absorption spectroscopies, 1H NMR and elemental analysis. The results of biological activity testing revealed that 4a and 4c had stronger inhibit action for Escherichia coli (CCTCC AB91115).
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