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1 临床资料 本组男婴5例,女婴3例,发病年龄为40天至3月,其中7例为母乳喂养,1例为混合喂养。临床表现:起病急,入院时主要表现为表情呆滞(4例),神志不清(4例),惊厥(7例),前囟饱满(7例),呻吟(3例),凝视(3例),瞳孔不等大(4例),面色苍白(7例),拒奶呕吐(7例),呼吸不规则(4例),全身其他部位出血(2例),有腹泻史5例,其中2例间断腹泻1个月以上,1例有血便。 实验室检查;Hb<7.0/d1,RBC<~3.0×l0~9/L有7例,血钙<2.24mmol/L2例,凝血酶元时间延长5例,2例做硬膜下穿刺为血性积液,7例腰穿均见血性脊液。入院时有3例分别误诊为毒痢、肠道感染、手足搐搦症,另3例为惊厥,原因待查,只有2例诊断本病。
1 Clinical data 5 cases of this group of baby boys, girls 3 cases, the age of 40 days to March, of which 7 cases of breastfeeding, 1 case of mixed feeding. Clinical manifestations: acute onset, mainly manifested as slow expression (4 cases), unconsciousness (4 cases), convulsions (7 cases), full bregma (7 cases), moaning (3 cases) (4 cases), pale face (7 cases), refuse milk vomiting (7 cases), irregular breathing (4 cases), bleeding in other parts of the body (2 cases), history of diarrhea in 5 cases, Two cases of intermittent diarrhea more than 1 month, 1 case of bloody stool. Laboratory examination; Hb <7.0 / d1, RBC <~ 3.0 × 10 ~ 9 / L in 7 cases, serum calcium <2.24mmol / L2 cases, prolonged prothrombin time in 5 cases, 2 cases of subdural puncture is bloody Fluid, seven cases of lumbar puncture were seen bloody spinal fluid. 3 cases were admitted to hospital were misdiagnosed as poisoning diarrhea, intestinal infections, tetany, the other three cases of convulsions, to be investigated, only 2 cases of the diagnosis of the disease.