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目的:研究THP(吡柔比星)对非肌层浸润性膀胱癌早期的定位诊断效果。方法:选择35例已诊断膀胱癌或高度怀疑尿路上皮癌患者。病人术前及术后复查时,30mgTHP溶入50ml 5%葡萄糖液中,灌入已排空的膀胱中,保留15分钟,排出THP,彻底冲洗膀胱。普通膀胱镜检查,有THP吸收的非肿瘤区域取活检,无THP吸收的部位随机活检。结果:35例患者中存在非肌层浸润性膀胱癌早期的共6例。结论:THP对非肌层浸润性膀胱癌早期的定位诊断效果明确,安全性好。
Objective: To study the early diagnosis and localization of THP (pirarubicin) on non-muscle invasive bladder cancer. Methods: 35 patients with bladder cancer or highly suspected urothelial carcinoma were selected. Patients preoperative and postoperative review, 30mgTHP dissolved in 50ml of 5% glucose solution, poured into the bladder has been emptied and retained for 15 minutes, the discharge of THP, flushing the bladder thoroughly. Common cystoscopy, non-tumor area with THP biopsy taken, no THP absorption of the site of random biopsy. Results: There were 6 cases of early non-muscle invasive bladder cancer in 35 patients. Conclusion: THP has definite effect on early diagnosis of non-muscle invasive bladder cancer with good safety.