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目的:研究相同剂量的罗哌卡因与布比卡因腰麻用于剖宫产手术的效应对比,探讨罗哌卡因腰麻用于剖宫产手术的有效性和安全性.方法:选择40例ASAⅠ-Ⅱ级行腹膜外剖宫产病人,22岁-39岁,随机分成两组.用0.75％罗哌卡因和布比卡因各2ml,分别加入10％葡萄糖1ml配成重比重溶液.采用25G腰麻穿刺针,于L3-L4间隙穿刺.在15s内恒速注入蛛网膜下腔药液2ml.比较两组病人在感觉、运动阻滞及恢复上的异同,由手术医生评定术中胍松程度,由病人评定镇痛情况,并观察病人用药后的不良反应.结果:两组病人的感觉阻滞起效时间、恢复时间、最高阻滞平面、最大阻滞时间无显著差异;罗哌卡因组的运动阻滞起效时间和最大运动阻滞时间比布比卡因组长(P<0.05),最大Bromagc评分也明显小于布比卡因组,运动恢复时间小于布比卡囡组(P<0.05).镇痛效果及肌松程度两组无显著差异(P>0.05).两组出现的心动过缓、低血压等不良反应发生相似. 结论:罗哌卡因可以安全、有效地用于腰麻下行剖宫产手术.
Objective: To study the effect of ropivacaine and bupivacaine for cesarean section at the same dose and to compare the efficacy and safety of ropivacaine for cesarean section.Methods: Forty ASAⅠ-Ⅱ patients underwent extraperitoneal cesarean section, aged 22 years -39 years old, were randomly divided into two groups.Their 2mls of 0.75% ropivacaine and bupivacaine were respectively added with 1ml of 10% .25G spinal needle was used to puncture L3-L4, and 2ml subarachnoid liquid was injected at a constant rate within 15s. The similarities and differences in sensory, motor block and recovery between the two groups were compared and evaluated by the surgeon The level of guanidine and analgesia were evaluated by the patient and the adverse reactions after the medication were observed.Results There was no significant difference in onset time, recovery time, maximal block level and maximal block time of sensory block between the two groups. The time of onset of motor block and the maximum block time of ropivacaine group were longer than that of bupivacaine group (P <0.05), and the maximum Bromagc score was significantly lower than that of bupivacaine group, and the recovery time was less than that of bupivacaine Group (P <0.05) .The analgesic effect and muscle relaxation degree had no significant difference between the two groups (P> 0.05) Bradycardia, hypotension and other adverse reactions similar conclusion: ropivacaine can be safely and effectively used for spinal anesthesia cesarean section.