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盐酸乙奎醚为新型抗胆碱药,具有选择性M_1、M_3和N_1、N_2受体拮抗作用,对中枢和外周均有很强的抗胆碱作用,而对M_2受体无明显作用,可有效避免阿托品缺乏M受体亚型选择性所致的心动过速与阻断突触前膜M_2受体调节功能。且药效长而副作用少。临床广泛使用,为了进一步评估其治疗胆绞痛的疗效及副作用,本研究用阿托品作对照,进行临床观察。
Acetochlor Hydrochloride is a new anticholinergic drug with selective antagonism of M_1, M_3 and N_1, N_2 receptors. It has a strong anticholinergic effect on the central and peripheral organs but has no obvious effect on the M_2 receptor, which can effectively prevent atropine Lack of M receptor subtypes selective tachycardia and block presynaptic membrane M 2 receptor regulatory function. And long-term efficacy and less side effects. Clinical widely used, in order to further evaluate its efficacy and side effects of treatment of biliary colic, atropine used in this study as control, for clinical observation.