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目的监测衢州市健康人群百日咳抗体,为制订科学的免疫方案和提高接种质量提供依据。方法分新生儿、2岁、3岁、4~5岁、6~7岁、8~10岁、11~15岁、16~25岁、26~35岁、36~59岁和≥60岁共11个年龄组,按随机抽样方法抽取30~50名监测对象,共采集357名健康人血清,采用Ig G抗体定量检测试剂盒(酶联免疫法)测定百日咳PT-Ig G。结果百日咳PT-Ig G抗体总阳性率为26.61%,百日咳各年龄组阳性保护率和GMC差异均有统计学意义(P<0.01)。结论百日咳PT-Ig G抗体阳性率较高,反映出取得了明显的流行病学效果,衢州市百日咳疫苗免疫接种有效。
Objective To monitor pertussis antibodies in healthy population of Quzhou city and provide basis for formulating scientific immunization programs and improving vaccination quality. Methods Newborns, 2 years old, 3 years old, 4 to 5 years old, 6 to 7 years old, 8 to 10 years old, 11 to 15 years old, 16 to 25 years old, 26 to 35 years old, 36 to 59 years old and ≥ 60 years old Eleven age groups were randomly selected from 30 to 50 samples were collected from a total of 357 healthy human serum Ig G antibody quantitative detection kit (enzyme-linked immunosorbent assay Pertussis PT-Ig G). Results The total positive rate of pertussis PT-Ig G antibody was 26.61%. There was significant difference between the positive rate of protective and GMC in all age groups (P <0.01). Conclusions The positive rate of pertussis PT-Ig G antibody is high, which shows that the epidemiological effect has been obtained. Vaccination with pertussis vaccine in Quzhou City is effective.