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对1992年4月~1993年8月天津市肿瘤医院乳腺科收治的女性乳腺癌患者63例,乳腺良性病变12例,叶状囊肉瘤3例,分别采用免疫组化法进行癌胚抗原(CEA)及c-erbB-2癌基因产物表达的测定。检测发现乳腺良性病变基本呈阴性着色,乳腺癌基本均为阳性或强阳性,增生性病变则多为弱阳性。少数HE染色尚未出现明显异型的重度乳头状瘤病和导管上皮不典型增生,其免疫组化CEA或c-erbB-2呈阳性或强阳性着色,符合病理组织学考虑这两种病变均已处于早期癌变阶段的见解。
From April 1992 to August 1993, 63 women with breast cancer were treated in the breast department of Tianjin Cancer Hospital. 12 cases of benign breast lesions and 3 cases of phyllodes cystosarcomas were treated with immunohistochemistry for carcinoembryonic antigen (CEA). And c-erbB-2 expression of oncogenic products. Detection found that benign breast lesions were basically negative, breast cancer was basically positive or strong positive, hyperplastic lesions are mostly weak positive. A few hematoxylin-eosin stains did not appear to have severe isotypes of severe papillomatosis and ductal epithelial dysplasia. The immunohistochemical staining of CEA or c-erbB-2 was positive or strongly positive, consistent with histopathological considerations. Early cancer stage insights.