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目的观察难治性癫痫对卒中后遗症的影响。方法选择脑卒中后难治性癫痫患者26例,其中全身强直-阵挛发作11例,部分性发作15例。对比观察癫痫发作前、后患者脑CT、神经功能缺损程度及记忆商数的变化。结果发现继发全身性发作患者癫痫发作后记忆商数明显下降,继发部分性癫痫发作患者神经功能缺损程度长时间持续恶化,但癫痫发作后患者脑CT检查无明显变化。结论部分性癫痫发作加重了患者原发的神经功能缺陷,全身强直-阵挛发作能够加重患者记忆障碍。
Objective To observe the impact of refractory epilepsy on stroke sequelae. Methods Twenty-six patients with intractable epilepsy after stroke were enrolled. Among them, 11 were systemic tonic-clonic seizures and 15 were partial seizures. The changes of brain CT, the degree of neurological deficits and the quotient of memory before and after epileptic seizure were observed. The results showed that patients with secondary generalized seizures patients after seizure significantly decreased the number of memory, secondary partial seizures in patients with neurological deficits continued to deteriorate for a long time, but after the onset of seizures in patients with no significant change in brain CT examination. Conclusion Partial seizures aggravate the primary neurological deficits in patients. Systemic tonic-clonic seizures can aggravate the memory impairment in patients.