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目的:探讨血清镁与非胰岛素依赖型糖尿病(NIDDM)的关系。方法:对50例NIDDM患者(其中42例伴有视网膜病变、肾脏病变、周围神经病变、冠心病、高血压)和100例正常对照者做血清镁测定。结果:NIDDM患者血清镁水平明显低于正常对照组(P<001);相关分析显示镁与空腹血糖、视网膜病变、血压显著负相关(r=-058、-056、-048,P<001)。结论:低血镁对糖尿病及其慢性并发症可能有不良影响。
Objective: To investigate the relationship between serum magnesium and non-insulin-dependent diabetes mellitus (NIDDM). Methods: Serum magnesium levels were measured in 50 patients with NIDDM (42 with retinopathy, nephropathy, peripheral neuropathy, coronary heart disease and hypertension) and 100 normal controls. Results: The level of serum magnesium in patients with NIDDM was significantly lower than that in controls (P <001). Correlation analysis showed that there was a significant negative correlation between magnesium and fasting blood glucose, retinopathy and blood pressure (r = -0.58, -0.56, 0 48, P <0 01). Conclusion: Hypomagnesemia may have adverse effects on diabetes mellitus and its chronic complications.