论文部分内容阅读
目的为提高急性脑卒中患者的免疫功能和防治医院感染。方法对４６例脑卒中伴发医院感染患者，采用抗生素及常规药物治疗２３例，与加用纳洛酮治疗２３例，同时观察其外周血淋巴细胞计数、血浆β－内啡肽含量。结果纳洛酮治疗组患者外周血淋巴细胞计数显著高于常规治疗组，而血浆β－内啡肽含量显著低于常规治疗组，医院感染控制时间也明显短于常规治疗组。结论纳洛酮可拮抗β－内啡肽对ＲＢＣ免疫功能的抑制作用，从而提高ＲＢＣ免疫功能，促进医院感染好转
The purpose is to improve the immune function of patients with acute stroke and prevention and treatment of nosocomial infections. Methods Twenty-six patients with nosocomial infection were treated with antibiotics and conventional drugs. Twenty-three patients were treated with naloxone, and the peripheral blood lymphocyte counts and the content of plasma β-endorphin were also observed. Results The counts of peripheral blood lymphocytes in naloxone treated group were significantly higher than those in the conventional treatment group, while the plasma levels of β-endorphin were significantly lower than those in the conventional treatment group. The nosocomial infection control time was also significantly shorter than that in the conventional treatment group. Conclusion Naloxone can antagonize the inhibitory effect of β-endorphin on the immune function of RBC, thereby enhancing the immune function of RBC and promoting the improvement of nosocomial infection