论文部分内容阅读
目的了解早产儿巨细胞病毒(HCMV)、弓形虫(TOX)、乙肝病毒(HBV)、单纯疱疹病毒1型(HSV-1)、单纯疱疹病毒2型(HSV-2)、风疹病毒(RV)与柯萨奇病毒B组3型(CVB3)的感染状况。方法采用巢式PCR对122例早产儿和75例正常新生儿进行7种病原体核酸的筛查检测。结果早产儿HCMV感染率为63.9%、TOX感染率为3.3%,HBV感染率为9.8%,HSV-1感染率为4.9%,HSV-2感染率为6.6%,RV感染率为3.3%,CVB3感染率为23.8%。早产儿HCMV、HBV、HSV-2和CVB3感染率与正常新生儿HCMV、HBV、HSV-2、CVB3感染率29.3%、1.3%、0和0比较,差异有统计学意义(P<0.05)。结论 HCMV、HBV、HSV-2和CVB3感染是早产儿发生的危险因素之一。
Objective To investigate the effects of prenatal cytomegalovirus (HCMV), TOX, HBV, HSV-1, HSV-2, RV, And Coxsackie virus group B type 3 (CVB3) infection status. Methods Nested PCR was used to screen seven pathogens in 122 premature infants and 75 normal newborns. Results The prevalence of HCMV in preterm infants was 63.9%, TOX infection rate was 3.3%, HBV infection rate was 9.8%, HSV-1 infection rate was 4.9%, HSV-2 infection rate was 6.6%, RV infection rate was 3.3%, CVB3 The infection rate was 23.8%. The infection rates of HCMV, HBV, HSV-2 and CVB3 in preterm infants were 29.3%, 1.3%, 0 and 0 respectively compared with normal neonates with HCMV, HBV, HSV-2 and CVB3 infection, the difference was statistically significant (P <0.05). Conclusion HCMV, HBV, HSV-2 and CVB3 infection are one of the risk factors in preterm infants.