Y染色体的微小缺失已经被公认为会影响精子的生成。随着分子生物学的发展,影响精子生成的基因位点被限定在3个不重叠的区域,称为“少弱精因子”(AZF)的区域。AZFa,b,c均靠近Y染色体长臂的远侧端。该试验的目的是调查畸精症患者的Y染色体是否有微小缺失。方法:将80例已确定为畸 The tiny deletion of the Y chromosome has been recognized as affecting sperm production. With the development of molecular biology, the gene loci affecting spermatogenesis are confined to three non-overlapping regions, called the region of “less weakly-degenerate” (AZF). AZFa, b, c are close to the distal end of the Y chromosome long arm. The purpose of this trial was to investigate whether there is a slight deletion of the Y chromosome in patients with teratosis. Methods: 80 cases have been identified as abnormal