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目的探讨部分脾动脉栓塞术对肝硬化的临床意义。方法经皮股动脉插管,至脾动脉部分分支进行栓塞,观察术后血常规、门静脉主干内径的变化及其不良反应。结果术后血小板及白细胞计数均明显增加(P<0.01);术后6个月门静脉内径明显缩小(P<0.01)。术后38例患者均出现不同程度发热、脾区疼痛,4例有胸腔积液,对症处理后全部缓解。结论部分脾动脉栓塞术治疗肝硬化门静脉高压症安全、有效、微创,值得临床推广。
Objective To investigate the clinical significance of partial splenic artery embolization on cirrhosis. Methods Percutaneous femoral artery cannulation, partial splenic artery embolization, observation of postoperative blood and portal vein diameter changes and adverse reactions. Results The postoperative platelet and leukocyte count were significantly increased (P <0.01). The diameter of portal vein was significantly reduced at 6 months after operation (P <0.01). Thirty-eight patients developed fever, spleen pain and pleural effusion in 4 patients, all of which were relieved after symptomatic treatment. Conclusion Some of the splenic arterial embolization for the treatment of cirrhosis and portal hypertension is safe, effective and minimally invasive, which is worthy of clinical promotion.