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目的探讨氨氯地平联合缬沙坦治疗肾性高血压临床疗效。方法选取我院2014年2月至2016年2月收治的患有肾性高血压的120例患者,将其按照住院的顺序分为对照组和观察组,对照组患者采用单一的氨氯地平治疗,观察组患者采用氨氯地平联合缬沙坦治疗,对比两组患者治疗后的效果。结果经过治疗后,两组患者的总有效率、血压、24h尿蛋白水平以及血肌酐均存在显著差异(P<0.05),有统计学意义。结论肾性高血压采用氨氯地平联合缬沙坦治疗疗效显著,对患者的肾脏进行有效的保护,降低患者的血压,可在临床上大力推广应用。
Objective To investigate the clinical efficacy of amlodipine combined with valsartan in the treatment of renal hypertension. Methods A total of 120 patients with renal hypertension admitted in our hospital from February 2014 to February 2016 were divided into control group and observation group according to the order of hospitalization. Patients in the control group were treated with single amlodipine , The observation group patients treated with amlodipine combined with valsartan, compared two groups of patients after treatment. Results After treatment, the two groups of patients with total effective rate, blood pressure, 24h urinary protein levels and serum creatinine were significantly different (P <0.05), with statistical significance. Conclusion Amlodipine combined with valsartan has a significant therapeutic effect on renal hypertension. It can effectively protect the kidney of patients and reduce the blood pressure of patients. It can be widely applied clinically.