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目的探究分析2型糖尿病患者血清脂联素与视网膜病变的关系。方法根据回顾性分析的方法随机抽取我院于2009年6月-2012年2月之间收治的2型糖尿病患者共100例,另30例为公务员体检中抽取的健康成人血清,对所有参加研究试验的人群进行血清脂联素含量测定,对比分析含量的区别及意义。分组方法为,所有2型糖尿病患者组成DM组,健康成人作为试验对照组,以NC表示。结果经过实验室血清脂联素检查,DM组患者整体血清脂联素水平低于对照组,且有统计学意义(P<0.05)。结论 2型糖尿病的发病过程与血清脂联素水平存在密切联系,一定程度上可以说血清脂联素的含量间接反映了2型糖尿病疾病进展程度,且研究还发现当2型糖尿病患者伴有视网膜疾病时血清脂联素的水平进一步降低,证明了2型糖尿病患者血清脂联素与视网膜病变之间的密切关系。
Objective To investigate the relationship between serum adiponectin and retinopathy in type 2 diabetic patients. Methods According to the method of retrospective analysis, we randomly selected 100 cases of type 2 diabetes mellitus patients admitted to our hospital from June 2009 to February 2012 and the other 30 cases of healthy adult sera sampled from the civil service examination. The test population of serum adiponectin content determination, comparative analysis of the content of the difference and significance. The grouping method consisted of DM patients in all type 2 diabetic patients and healthy adults as test control group and NCs. Results After the serum adiponectin was tested in laboratory, the level of serum adiponectin in DM group was lower than that in control group (P <0.05). Conclusions The pathogenesis of type 2 diabetes is closely related to serum adiponectin level. To some extent, it can be said that the content of serum adiponectin indirectly reflects the degree of progression of type 2 diabetes mellitus. The study also found that when the type 2 diabetes patients with retinal Serum adiponectin levels were further reduced in the disease, demonstrating a close relationship between serum adiponectin and retinopathy in patients with type 2 diabetes.