喉癌喉咽癌哨位淋巴结的临床初步研究

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目的 探讨喉癌喉咽癌哨位淋巴结的检测及其对颈淋巴结转移的预测价值。方法 用手术中注射蓝染料的方法 ,对 2 9例颈淋巴结N0的喉癌喉咽癌患者进行了哨位淋巴结的临床研究。手术中取蓝染的哨位淋巴结作快速冰冻病理检查 ,并与HE染色病理检查结果及颈清扫切除的淋巴结病理检查对照 ,观察哨位淋巴结转移对颈淋巴结转移癌的预测值。结果  2 9例中 2 8例成功地显示了哨位淋巴结 ,成功率达 96 .6 %。每例发现蓝染的哨位淋巴结 1~ 4个 ,平均每例每侧检出 2 .5个。有 3例患者的哨位淋巴结检测有肿瘤转移 ,HE染色病理检查及颈清扫切除的淋巴结病理检查均证实颈淋巴结转移。 2 5例哨位淋巴结冰冻病理检查阴性患者 ,颈淋巴结清扫标本亦未查见淋巴结转移。哨位淋巴结对颈淋巴结转移的阳性预测正确率和阴性预测率均为 10 0 %。结论 哨位淋巴结检测对喉癌喉咽癌的颈淋巴结转移有重要的预测价值 Objective To investigate the detection of laryngeal cancer laryngeal cancer sentinel lymph nodes and its predictive value for cervical lymph node metastasis. Methods The method of injecting blue dye in operation was used to study the sentinel lymph nodes in 29 laryngeal cancer patients with laryngeal carcinoma of the neck with lymph node N0. Surgical blue-stained sentinel lymph nodes for rapid frozen pathological examination and pathological examination with HE staining and neck dissection resection of lymph node pathological examination control, observation of sentinel lymph node metastasis of cervical lymph node metastases prediction. Results Twenty-nine of 29 cases successfully showed sentinel lymph nodes with a success rate of 96.6%. Each case found blue stained sentinel lymph nodes 1 to 4, an average of each side detected 2. 5 per case. There were 3 cases of sentinel lymph node metastasis detection, pathological examination of HE staining and neck dissection resection of lymph node pathology confirmed cervical lymph node metastasis. 25 cases of sentinel lymph node negative pathological examination, cervical lymph node dissection specimens did not check the lymph node metastasis. The positive predictive value and negative predictive value of sentinel lymph node versus cervical lymph node metastasis were 100%. Conclusion The sentinel lymph node detection has important predictive value for cervical lymph node metastasis of laryngeal carcinoma
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