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我院妇产科门诊自1998年6月12日至30日,对孕6至10周的孕妇,无其它合并症,愿意接受无痛人流术者共52例,随机分为A、B两组。A组13例肌注氯胺酮麻醉,B组39例肌注芬太尼镇痛,两组均肌注2.5mg氟哌啶协同作用。实验结果:氯胺酮为麻醉镇痛药,使病人意识丧失,肌注最小有效是为80mg,清醒后部分病人有恶心呕吐等副反应,而且术后观察时间长,引起家属焦虑,给医务工作者增加工作负担。不适用于门诊病人。芬太尼为强镇痛药,不影响神志,肌注最小有效量为0.1mg,无明显副反应,故使用方便,利于观察,安全有效,为较理想的人流镇痛药物,值得临床推广应用。
Obstetrics and gynecology clinic in our hospital from June 12, 1998 to 30, pregnant 6 to 10 weeks pregnant women, no other complications, are willing to accept a total of 52 cases of painless abortion, were randomly divided into A, B two groups . A group of 13 cases of intramuscular injection of ketamine anesthesia, B group 39 cases of intramuscular injection of fentanyl analgesia, intramuscular injection of 2.5mg haloperidol synergies. Experimental results: Ketamine for narcotic analgesics, the loss of patient consciousness, intramuscular injection of the smallest effective is 80mg, awake after some patients nausea and vomiting and other side effects, and postoperative observation of a long time, causing anxiety in families, to medical workers to increase Work load. Not suitable for outpatients. Fentanyl is a strong analgesic, does not affect the mind, intramuscular injection of the minimum effective dose of 0.1mg, no obvious side effects, it is easy to use, conducive to observation, safe and effective for the more ideal flow of analgesics worthy of clinical application .