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良性颅高压(假性脑瘤),是一组以颅高压的体征和症状为特征的综合征,没有局灶性病变的临床及神经放射学体征,亦无脑室扩张改变.除了临床症状之外,诊断是依据CSF压力经常增高超过正常范围而确定.此外,临床诊断应有1～2年的观察时间.颅内压增高的病理生理至今未明.颅内哪一部分(血、脑或CSF)首先受累尚不清楚.然而,新近进展的许多致病假说中,作者认为其中两个似乎特别有讨论价值.第1个是Mathew等所提出:认为某些病人的症状首先是血脑屏障发生改变,并有膜的运输系统变化.这种可能性可以解释当内分泌紊乱、低血钙或使用某些药物后(四环素、Nalidixic Acid)可导致假性脑瘤的发生.第二种假说是Johnston(1973年)所提出的,认为所有病例的症状都是
Benign intracranial hypertension (pseudo-brain tumor) is a group of syndromes characterized by signs and symptoms of intracranial hypertension without clinical and neuroradiologic signs of focal lesions and no changes in ventricular dilatation. In addition to clinical symptoms , The diagnosis is based on the CSF pressure is often higher than the normal range to determine. In addition, the clinical diagnosis should be 1 to 2 years of observation. Increased intracranial pressure pathophysiology has not yet been identified which part of the intracranial (blood, brain or CSF) However, recent reviews of many pathogenicity hypotheses suggest that two of these authors appear to be of particular value to the discussion: The first, proposed by Mathew et al., States that some patients’ symptoms are primarily blood-brain barrier changes, And the membrane transport system changes.This possibility may explain the endocrine disorders, hypocalcemia or the use of certain drugs (tetracycline, Nalidixic Acid) can lead to pseudo-brain tumor.The second hypothesis is Johnston (1973 Year), all the symptoms of the case are considered