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血清磷酸肌酸激酶(CPK)活性降低常不被人注意。本文报告急性病毒性肝炎(AVH)患者CPK值降低,而肝外阻塞性黄疸(obstructive jaundice,OJ)患者CPK水平正常。 3组人员参加了研究:①A组为过去2年期间住院的27(男15、女12)例诊断为AVH的患者,平均年龄38(14～78)岁。其中19例有AVH的典型表现,9例HBsAg阳性;其余8例经肝活检证实。所有患者作超声检查和胆道放射性核素显象均未发现肝外阻塞。②B组为25(男11、女14)例手术时诊断为肝外OJ的患者,平均年龄58(22～88)岁,其中恶性肿癌患者手术时均未发现肝转移。③对照组为26(男13、女13)例健康志愿者,平均年龄41(16～78)岁。A组和B组患者于住院期间5次测定血清胆红
Serum creatine phosphokinase (CPK) activity is often not noticed. This article reports a decrease in CPK values in patients with acute viral hepatitis (AVH) and normal CPK in patients with obstructive jaundice (OJ). Three groups of participants participated in the study: ①A group of 27 patients (15 males and 12 females) hospitalized with AVH over the past 2 years with a mean age of 38 (14 to 78) years. Of these, 19 had typical AVH manifestations and 9 had HBsAg positive; the remaining 8 were confirmed by liver biopsy. All patients underwent ultrasonography and biliary radionuclide imaging showed no extrahepatic occlusion. ②B group 25 (male 11, female 14) cases were diagnosed as extrahepatic OJ during surgery, with an average age of 58 (22 to 88) years old, in which patients with malignant tumor surgery were not found in liver metastases. ③ The control group was 26 (male 13, female 13) healthy volunteers with an average age of 41 (16-78) years. Patients in groups A and B measured serum bilirubin five times during hospitalization