目的　了解四川省西昌市吸毒人群吸毒方式及性行为特征与HCV感染的关系。方法　于2 0 0 4 - 0 5 / 0 7,调查四川省西昌市吸毒人群的社会人口学、吸毒方式及性行为特征与HCV感染的关系。采集血样进行HCV和梅毒抗体检测。结果　在调查的吸毒人群6 19人中,HCV感染率为5 5 .9% (346 / 6 19) ,其中静脉吸毒者的HCV感染率为71 9% (2 35 / 32 7)。在单因素和多因素分析中,曾经静脉注射吸毒(OR =2 .6 3;95 %CI为1 .79～3 .89,P <0 .0 0 1)和曾经共用针头或注射器具吸毒(OR =2 .98,95 %CI为1 .78～5 . 0 0 ,P <0 . 0 0 1)与HCV感染有统计学意义。结论　吸毒人群HCV感染与其高危吸毒行为有关。 Objective To investigate the relationship between drug abuse patterns and sexual behavior among HCV drug users in Xichang, Sichuan Province. Methods The population of drug users in Xichang City of Sichuan Province were surveyed on the basis of socio-demography, drug abuse patterns and sexual behaviors with HCV infection. Blood samples were collected for HCV and syphilis antibody testing. Results Of the 6 19 drug users surveyed, the HCV infection rate was 55.9% (346/6 19), of which 71 9% (2 35/32 7) were infected by intravenous drug users. In univariate and multivariate analyzes, those who had had intravenous drug use (OR = 2.63; 95% CI, 1.79 to 3.89, P <0.001) and those who had shared needles or syringes OR = 2.98, with a 95% CI of 1.78-5.00, P <0.001) and HCV infection were statistically significant. Conclusion HCV infection in drug addicts is associated with high-risk drug use.