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目的采用益气解毒活血法加化疗治疗急性髓细胞白血病并院外随访随访,观察其对成人AML微小残留白血病的影响。方法按数字表法随机分为治疗组和对照组各60例,完全缓解后对照组以DA、HA、HD-AraC、MA交替序贯治疗,治疗组在常规化疗基础上,间歇期加用益气解毒活血中药治疗。结果2组患者组内比较MRD检出率均与CR维持时间呈负相关,随CR维持时间延长而降低,2组患者组间比较MRD检出率,治疗组明显低于对照组,差异有显著性。(P<0.05)。结论益气解毒活血法联合化疗对成人AML微小残留白血病细胞具有良好的抑制其增殖的作用。
Objective To observe the effect of Yiqi Jiedu Huoxue plus chemotherapy on acute myeloid leukemia and follow-up in hospital during the follow-up period to observe its effect on minimal residual leukemia in adults. Methods According to the digital table method, 60 cases were randomly divided into treatment group and control group. After complete remission, the control group was alternately treated with DA, HA, HD-AraC and MA. On the basis of routine chemotherapy, Detoxification and blood circulation Chinese medicine treatment. Results The detection rates of MRD in both groups were negatively correlated with the duration of CR maintenance and decreased with the duration of CR maintenance. The detection rates of MRD in two groups were significantly lower than those in the control group, the difference was significant Sex. (P <0.05). Conclusion Yiqi Jiedu Huoxue Decoction combined with chemotherapy has a good inhibitory effect on the proliferation of adult AML minimal residual leukemia cells.