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目的探讨光纤导入瘤体内NGPDT照射治疗中、晚期肝癌的应用价值。方法选取56例中晚期肝癌患者为研究对象,在B型超声引导下,采用18G肝穿刺针穿刺进肝肿瘤内,导入光纤行分区布点照射治疗。结果56例肝癌患者中,1年生存率26.79%(15/56),2年生存率7.14%(4/56),3年生存率7.14%(4/56),5年及以上生存率3.57%(2/56)。治疗效果与NGPDT治疗次数、肝癌组织分型有关,而与甲胎蛋白(AFP)定量无关。结论NGPDT治疗中晚期肝癌能够有效延长患者的生存时间,应加强其应用的研究。
Objective To investigate the value of optical fiber guided NGPDT irradiation in the treatment of advanced and advanced liver cancer. Methods Fifty-six patients with advanced hepatocellular carcinoma (HCC) were enrolled in this study. Under the guidance of B-mode ultrasound, 18G hepatic puncture needle was used to puncture the liver tumor. Results Among the 56 patients with HCC, the 1-year survival rate was 26.79% (15/56), the 2-year survival rate was 7.14% (4/56), the 3-year survival rate was 7.14% (4/56), and the 5-year survival rate was 3.57 % (2/56). The therapeutic effect is related to the number of NGPDT treatment and the classification of HCC tissue, but not to the quantitative determination of AFP. Conclusion NGPDT in the treatment of advanced hepatocellular carcinoma can effectively prolong the survival time of patients, and its application should be strengthened.