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目的 :探讨高海拔移居低海拔人群与世居低海拔人群高血压相关疾病发生率的异同。方法 :调查从西藏高原 (海拔 30 0 0米以上 )移居四川省成都市且住地相对集中的汉族人群罹患高血压者 10 8例为研究对象 ,世居成都市人群罹患高血压 12 1例为对照组 :通过询问病史、查体和采集空腹静脉血测定血糖、血脂、血尿酸以及心电检查或选择性冠脉造影、脑CT(或MRI) ,就两组高血压相关疾病发生率进行比较 ,所有数据采用卡方检验 ,P≤ 0 .0 5表示有显著性差异。结果 :高血压相关疾病中糖尿病、脂代谢异常、高尿酸血症、冠心病及脑卒中两组差异均无显著性 (P >0 .0 5 )。结论 :高海拔移居低海拔人群高血压各相关疾病患病率与世居低海拔人群接近 ,故高海拔移居低海拔人群高血压相关疾病的防治工作应与世居内地人群同等重视
Objectives: To explore the similarities and differences in the incidence of hypertension-related diseases in high-altitude displaced low-altitude populations and in low-altitude populations. METHODS: A total of 108 patients with hypertension from the Tibetan Plateau (above 300 m altitude) who migrated to Chengdu, Sichuan province and had relatively concentrated settlements were investigated. Among the population, 12 1 were living with hypertension. Group: The incidence of hypertension-related diseases was compared between the two groups by asking history, physical examination, and collecting fasting venous blood to determine blood glucose, blood lipids, serum uric acid, and ECG or selective coronary angiography, or brain CT (or MRI). All data were tested using chi-square test. P ≤ 0 . 0 5 indicates significant difference. Results: There was no significant difference in hypertension-related diseases such as diabetes, dyslipidemia, hyperuricemia, coronary heart disease, and stroke (P > 0.05). Conclusion : The prevalence of hypertension-related diseases is similar to that of low-altitude people living in high-altitude migrating low-altitude populations. Therefore, prevention and treatment of hypertension-related diseases in high-altitude people migrating to low-altitude population should be as important as those in the inland population.