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目的 通过研究神经肌炎患者的临床及病理特点来探讨神经肌炎能否作为一种独立的疾病实体。方法 分析26例神经肌炎的临床和病理改变。结果 神经肌炎的主要临床表现为肢体无力、疼痛、肌萎缩。15例肌酶正常,11例肌酶增高,以CK增高为主。肌电图可表现为神经源性损害和/或肌源性损害。病理活检可见神经肌肉大量炎性细胞浸润,神经脱髓鞘改变。结论 神经肌炎与多发性肌炎相比有其独特之处,神经肌炎作为一种独立的疾病,诊断主要依靠肌电图和病理。
Objective To investigate whether neuromuscular inflammation can serve as an independent disease entity by studying the clinical and pathological features of patients with neuromyositis. Methods The clinical and pathological changes of 26 cases of neuromyositis were analyzed. Results The main clinical manifestations of neuromyositis were limb weakness, pain and muscle atrophy. 15 cases of normal muscle enzymes, 11 cases of muscle enzymes increased to CK increased mainly. Electromyography can manifest as neurogenic damage and / or myogenic damage. Pathological biopsy shows a large number of neuromuscular inflammatory cell infiltration, demyelinating nerve changes. Conclusions Neuromyositis has its uniqueness compared with polymyositis. Neuromyositis is an independent disease that depends mainly on electromyography and pathology.