丙戊酸钠为一种不含氮的广谱抗癫痫药,可用于多种癫痫病发作的治疗,但最适用于全身性发作,如失神发作、全身性强直阵挛发作、失张力发作,亦可适用于部分性发作以及少年型肌阵挛癫痫、婴儿痉挛、Lennox综合征等。此外,本药对高热惊厥的复发有预防作用,多用于其他抗癫痫药治疗无效的各类型癫痫病人。该药口服吸收快,作用完全,主要分布在细胞外液,在血中大部分与血浆蛋白结合,有效血药浓度为50～100μg/ml。在抗癫痫的药物治疗中,一般遵循单一用药原则,多数病例单独应用一种药物即可取得满意疗效,但顽固的癫痫有时需合并用药,而抗癫痫药物的合用,往往存在着药物间的相互作用,引起血药浓度的波动, Sodium valproate is a non-nitrogen broad-spectrum antiepileptic drug that can be used for the treatment of many epileptic seizures but is best suited for generalized seizures such as absence seizures, generalized tonic clonic seizures, Can also be applied to partial seizures and juvenile myoclonic epilepsy, infantile spasms, Lennox syndrome. In addition, the drug on the recurrence of febrile seizures have a preventive effect, and more for other anti-epileptic drugs ineffective treatment of all types of epilepsy patients. The drug oral absorption fast, full effect, mainly in the extracellular fluid, most of the blood plasma protein binding, the effective plasma concentration of 50 ~ 100μg / ml. In anti-epileptic drug therapy, generally follow the principle of single medication, the majority of cases alone can achieve satisfactory results with a single drug, but stubborn epilepsy sometimes need to be combined with medication, and the combination of antiepileptic drugs, there is often the interaction between drugs Role, causing blood concentration fluctuations,