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蕈样肉芽肿（MF）是一种低度恶性的皮肤T细胞淋巴瘤。淋巴细胞恶性增殖的主要特点是克隆性增殖，在T淋巴瘤表现为TCR的单克隆性重排，而绝大多数炎症及反应性淋巴细胞浸润则是表现为多克隆性的。根据此点，近十几年来，国外用Southern杂交或聚合酶链反应检测皮损的T淋巴细胞的
Mycosis fungoides (MF) is a low-grade cutaneous T-cell lymphoma. Malignant proliferation of lymphocytes is characterized by clonal proliferation in T lymphoma showed TCR monoclonal rearrangement, while the vast majority of inflammatory and reactive lymphocyte infiltration is polyclonal. According to this point, nearly a decade, foreign Southern hybridization or polymerase chain reaction detection of lesions of T lymphocytes