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Ames试验是利用鼠伤寒沙门氏菌的营养缺陷型菌株,在有微粒体酶系统参与活化的条件下发生回复突变的性能来检测化学物质致突变性的一种测试方法。资料表明,用Ames法测得的致突变物之90%亦为致癌物。由于该法具有快速、简易、经济、尤其是准确度高等特点,可作为初步筛选潜在致癌物的一种方法,用于检测人类
Ames test is the use of Salmonella typhimurium auxotrophic strains, microsomal enzymes involved in the activation of the conditions under the conditions of the performance of mutations to detect chemical mutagenicity of a test method. Data show that 90% of the mutagens measured by the Ames method are also carcinogens. As the method is fast, simple, economical and especially accurate, it can be used as a preliminary screening method for potential carcinogens to detect human