药疹是指药物通过各种途径进入人体后引起皮肤黏膜的炎症反应,严重时可出现全身症状,累及内脏,甚至危及生命。近年来,AIDS/HIV感染患者生存率逐年提高的同时,其治疗中常用药物所引发的药疹也渐渐引起了临床医师的关注。由于AIDS/HIV感染患者免疫功能受到严重破坏,其药疹特点亦与常见药疹有很大不同,如潜伏期较HIV阴性人群更长,发病率更高,且重型药疹如SJS和TEN的发病率也远远高于HIV阴性人群。女性AIDS/HIV感染患者或CD4~+T细胞计数较高的患者可能具有更高的罹患药疹风险等。 Drug eruption refers to the drug through various channels into the human body caused by inflammation of the skin and mucous membranes, severe systemic symptoms may occur, involving the internal organs, and even life-threatening. In recent years, the survival rate of AIDS / HIV infection patients increased year by year at the same time, the drug commonly used in the treatment of drug eruption also gradually attracted the attention of clinicians. Due to severe damage to immune function in AIDS / HIV-infected patients, their drug eruptions are quite different from common drug eruptions such as longer latency and higher morbidity than HIV-negative individuals and the incidence of heavy drug eruptions such as SJS and TEN is also far behind Far higher than the HIV-negative population. Women with AIDS / HIV infection or those with high CD4 ~ + T cell counts may be at higher risk for drug eruptions.