大量流行病学资料已经确认,吸烟是引起猝死的一个独立的危险因素。作者对38岁到73岁(56.8±8.3)习惯性吸烟的男子,分成A、B两组进行基础电生理测试。A组13例大多因心绞痛而长期应用β-阻滞剂(普荼洛尔7例,美托洛尔6例)。其中4例剂量较大,故β-受体阻滞作用近乎完全;B组9例未应用β-阻滞剂。两组受试者均经插管作冠状动脉造影和电生理测试。除A组多支冠状动脉病变较B组为多见外(11/13,85％对3/9,33％,p <0.05),A、B两组的临床表现和基础电生理参数均无显著差别。作基础电生理测试的方法:插管进行心房和心室短阵调搏,周期自600至300ms,每次递减50ms,然后将调搏周期固定为500ms,给予单、双或叁次期前刺激,逐次提前10ms,直到有效不应期为止。基础电生理测试表明,A、B两组吸烟的电生理 A large number of epidemiological data have confirmed that smoking is an independent risk factor for sudden death. The authors divided men aged 38-73 years (56.8 ± 8.3) who were habitually smokers into groups A and B for basic electrophysiological testing. A group of 13 patients mostly due to angina and long-term use of β-blockers (propranolol in 7 cases, metoprolol in 6 cases). Among them, 4 patients had a large dose of β-blocker, and 9 patients in group B did not use β-blocker. Two groups of subjects were intubated coronary angiography and electrophysiological testing. The clinical manifestations and basic electrophysiological parameters of group A and B had no significant difference except group A with multiple coronary artery lesions more common than group B (11/13, 85% vs 3/9, 33%, p <0.05) Significant difference. Methods for basic electrophysiological testing: intubation of atrial and ventricular pacing, the cycle from 600 to 300ms, each decreasing 50ms, and then the cycle of the fixed 500ms, to give single, double or triple pre-stimulation, one by one 10ms in advance, until the effective should not date. Basic electrophysiological tests showed that electro-physiology of smoking in A and B groups