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背景在西方国家,胰腺癌是第四位肿瘤相关死亡的疾病。胰腺癌在获得确诊时,仅20%的患者能获得手术切除,而40%的患者因肿瘤局部进展而失去手术机会,另外40%的患者因远处转移无法手术切除。肿瘤局部进展无法手术切除的患者中位生存时间为9~15个月。此类患者除了化疗、放疗之外,射频消融治疗可能是改善预后的又一治疗选择,本文就其有效性及安全性进行系统回顾分析。方法在PubMed,EMBASE和考克兰图书馆中进行系统的文献检索,检索时使用词组“(射频或者射频消融)和(胰腺或者胰腺
Background In western countries, pancreatic cancer is the fourth cancer-related death. At diagnosis, only 20% of patients with pancreatic cancer have surgical resection, while 40% lose the chance of surgery due to local tumor progression. Another 40% of patients are not surgically removed due to distant metastases. The median survival time for patients with locally advanced unresectable tumors was 9-15 months. In addition to chemotherapy and radiotherapy, radiofrequency ablation of these patients may be another treatment option to improve the prognosis. In this paper, we systematically reviewed the effectiveness and safety of radiofrequency ablation. METHODS: A systematic literature search was performed in the PubMed, EMBASE and Cockcroft libraries using the phrase ”(radiofrequency or radiofrequency ablation) and (pancreas or pancreas