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目的:研究采用低分子肝素、阿司匹林、丹参滴丸联合用药方法对高原红细胞增多症的治疗效果。方法:对生活在海拔3000m~4000m地区的106例高原红细胞增多症病人随机分为对照组和治疗组。对照组采用丹参滴丸治疗;治疗组采用低分子肝素、阿司匹林、丹参滴丸联合用药方案治疗。治疗时间为12个月。分别在第6个月和第12个月进行随访,比较两组血红蛋白、血小板压积和血小板计数的变化情况,根据两组的变化差别来认识联合用药的治疗效果。结果:采用低分子肝素、阿司匹林、丹参滴丸联合用药方案对高原红细胞增多症的治疗较单独用丹参滴丸的治疗效果有明显的提高。结论:两组在第6个月和第12个月均出现明显的疗效差别(P<0.05)。
Objective: To study the therapeutic effect of low molecular weight heparin, aspirin, danshen dripping pills on the treatment of high altitude polycythemia. Methods: A total of 106 patients with high altitude polycythemia living in 3000m ~ 4000m above sea level were randomly divided into control group and treatment group. The control group was treated with Danshen Dripping Pills; the treatment group was treated with low molecular weight heparin, aspirin and Danshen dripping pills in combination with drug regimen. Treatment time is 12 months. The patients were followed up at the 6th month and the 12th month respectively. The changes of hemoglobin, platelet pressure and platelet count were compared between the two groups. According to the difference between the two groups, the therapeutic effects of combination therapy were recognized. Results: The treatment of high altitude polycythemia with low molecular weight heparin, aspirin and Danshen dripping pills was significantly better than the treatment with Danshen dripping pills alone. Conclusion: There was a significant difference in efficacy between the 6th month and the 12th month (P <0.05).