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目的探讨内镜下碘染色对Barrett食管的诊断价值。方法将内镜下考虑Barrett食管的病人82例随机分成两组,其中一组43例行碘染色后取活检,一组39例行常规内镜下活检。结果43例经内镜下碘染色后活检,病理诊断Barrett食管的为29例(66.44%),而常规内镜下活检诊断Barrett食管的为13例(33.33%),碘染色组的检出率明显高于非染色组,且经ROC曲线分析,内镜下碘染色组的ROC曲线下面积、灵敏度、特异度、阳性预测值和准确度明显高于常规内镜检查组。结论内镜下碘染色有助于提高Barrett食管的诊断率,在Barrett食管的诊断上具有重要的临床价值。
Objective To investigate the diagnostic value of endoscopic iodine staining in Barrett’s esophagus. Methods Eighty-two patients undergoing endoscopic resection of Barrett’s esophagus were randomly divided into two groups. One group of 43 patients underwent iodine staining and the other 39 patients underwent routine endoscopic biopsy. Results 43 cases were diagnosed by endoscopic iodine staining, the pathological diagnosis of Barrett ’s esophagus was 29 cases (66.44%), while the conventional endoscopic biopsy diagnosis of Barrett’ s esophagus was 13 cases (33.33%). The detection rate of iodine staining The area under the ROC curve, sensitivity, specificity, positive predictive value and accuracy of endoscopic iodine staining were significantly higher than those of the conventional endoscopy group by ROC curve analysis. Conclusion Endoscopic iodine staining is helpful to improve the diagnosis rate of Barrett’s esophagus and has important clinical value in the diagnosis of Barrett’s esophagus.